Lactic Acid → Decyl lactate

HRID 2380180

反応式

HRID 2380180 の反応式
[C:1]([OH:6])(=[O:5])[CH:2]([CH3:4])[OH:3].[CH2:7](O)[CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16].S(=O)(=O)(O)O>C1(C)C=CC=CC=1>[C:1]([O:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16])(=[O:5])[CH:2]([CH3:4])[OH:3]

参加物

5

反応物 3

HCID 612Lactic AcidHCID 1118Sulfuric AcidHCID 81741-Decanol

生成物 1

HCID 347720Decyl lactate収率 13.9%

試薬・触媒・溶媒 1

HCID 1140Toluene溶媒

反応条件

温度
145 °C

実験手順

A 500 mL one neck round bottom flask equipped with a Dean Stark trap, condensor and nitrogen inlet/outlet was charged with 22.52 g (0.75 moles) lactic acid, 47.46 g (0.98 moles) decyl alcohol, 3 ml sulfuric acid and 220 mL toluene. The mixture was heated to 145° C. for 20 hours and water was collected as the reaction proceeded. The acid was neutralized by washing three times with 50 ml saturated sodium bicarbonate solution. The organic layer was collected and dried over magnesium sulfate. Decyl lactate was distilled under high vacuum to yield 24.03 g (12.4% yield) of clear colorless liquid. According to GC the product is 97.78% pure.

後処理

  1. customwater was collected as the reaction
  2. washby washing three times with 50 ml saturated sodium bicarbonate solution
  3. customThe organic layer was collected
  4. dry with materialdried over magnesium sulfate
  5. distillationDecyl lactate was distilled under high vacuum

出典と根拠

ORDレコード
ord-cac6b32a9613412f9ee0a7b67ba8453b
出典データセット
uspto-grants-1994_11
特許番号
US05366665

関連ノート

読み込み中…