2,6-Dimethylaniline → N-(2,6-Dimethylphenyl)formamide

HRID 2381052

反応式

HRID 2381052 の反応式
[C:1]([O-:4])(=O)C.[Na+].[CH3:6][C:7]1[CH:13]=[CH:12][CH:11]=[C:10]([CH3:14])[C:8]=1[NH2:9]>C(O)=O>[CH3:6][C:7]1[CH:13]=[CH:12][CH:11]=[C:10]([CH3:14])[C:8]=1[NH:9][CH:1]=[O:4]

参加物

4

反応物 2

HCID 68962,6-DimethylanilineHCID 517045Sodium Acetate

生成物 1

HCID 345859N-(2,6-Dimethylphenyl)formamide収率 79%

試薬・触媒・溶媒 1

HCID 284Formic Acid溶媒

実験手順

4.1 10.0 g of sodium acetate are dissolved in 120 ml of formic acid. 50.0 g of 2,6-dimethylaniline 11 are then introduced, and the mixture is stirred under reflux for 24 h. The mixture is subsequently subjected to conventional work-up, giving 48.9 g (79%) of N-(2,6-dimethylphenyl)formamide 12; MS-EI (M+)=149.

後処理

  1. temperatureunder reflux for 24 h

出典と根拠

ORDレコード
ord-ecafce52565e444bbd417d8c3ac09ba6
出典データセット
uspto-grants-2012_09
特許番号
US08258151B2

関連ノート

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