Aniline → Pyridine-3-sulfonic acid [5-bromo-2-chloro-phenyl]-amide

反応式

[Br:1][C:2]1[CH:3]=[CH:4][C:5]([Cl:12])=[C:6](S(Cl)(=O)=O)[CH:7]=1.[N:13]1[CH:18]=[CH:17][CH:16]=[C:15]([S:19](Cl)(=[O:21])=[O:20])[CH:14]=1.[NH2:23]C1C=CC=CC=1>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([Cl:12])=[C:6]([NH:23][S:19]([C:15]2[CH:14]=[N:13][CH:18]=[CH:17][CH:16]=2)(=[O:21])=[O:20])[CH:7]=1

参加物

反応物 3

HCID 6115Aniline

HCID 3164136Pyridine-3-sulfonyl chloride

HCID 509888345-Bromo-2-chlorobenzene-1-sulfonyl chloride

生成物 1

HCID 62907758Pyridine-3-sulfonic acid [5-bromo-2-chloro-phenyl]-amide

実験手順

This compound is prepared analogously to Intermediate E (step 2), by replacing 5-bromo-2-chloro-benzenesulfonyl chloride in this procedure with pyridine-3-sulfonyl chloride and aniline with S-bromo-2-chloroaniline to afford the title compound.

出典と根拠

ORDレコード: ord-0cfcef6a44a64a2c8d1ce219f9fc0c39
出典データセット: uspto-grants-2012_09
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08263585B2

反応ノート

読み込み中…