化工社化工社 化学情報印刷レポート · 研究参考用
Cumene → 2-Phenyl-2-propanol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Cumene | HCID 7406 | — |
| 反応物 | N-Hydroxyphthalimide | HCID 10665 | — |
| 生成物 | Phenol | HCID 996 | 10.4% |
| 生成物 | Cumene | HCID 7406 | — |
| 生成物 | Acetophenone | HCID 7410 | — |
| 生成物 | 2-Phenyl-2-propanol | HCID 12053 | 13.1% |
反応手順
0.3 mmol of N-hydroxyphthalimide and 0.3 mmol of Co(II) acetate are added at a temperature of 125° C. to 30 mmol of cumene in a round-bottomed flask having an attached reflux condenser. The reaction mixture is stirred for 8 hours at said temperature under an oxygen atmosphere of 1 bar. Not the target product, but acetophenone is obtained at a selectivity of 58.7%, 2-phenyl-2-propanol (13.1%) and phenol (10.4%) at a cumene conversion rate of 49.3%.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06852893B2 |
| 出典データセット | uspto-grants-2005_02 |
| ORD ID | ord-2c65b7ac54fc4b36890f2034db340da0 |
| 出典メモ | uspto-grants-2005_02 |