関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Diethanolamine | HCID 8113 | — |
| 反応物 | Sodium Methoxide | HCID 10942334 | — |
| 反応物 | methyl 3-(N-vinylformamido)propionate | HCID 10964771 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | N,N-di-(2-hydroxyethyl) 3-(N-vinylformamido)propionamide | HCID 53864890 | — |
反応手順
A 50 mL single-neck round bottom flask equipped with a distillation head was charged with 15.1 grams (0.096 mole) of methyl 3-(N-vinylformamido)propionate, 9.95 grams (0.09 mole) of diethanolamine and 0.15 gram of 25% sodium methoxide in methanol solution. The mixture was stirred at 90° C. for 2 hours and the generated methanol was removed by distillation at reduced pressure. Both proton NMR and GC analyses indicated approximately a 90% conversion to the titled product.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US05728878 |
|---|
| 出典データセット | uspto-grants-1998_03 |
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| ORD ID | ord-5d0de86ea40e4c07a7ac73d256823ecf |
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| 出典メモ | uspto-grants-1998_03 |
|---|
