HCID 67309189、化合物 → HCID 15539217、化合物

HRID 2383335ノート

反応式

HRID 2383335 の反応式
Br[C:2]1[C:3]([CH3:16])=[CH:4][CH:5]=[C:6]2[C:11]=1[CH:10]=[C:9]([C:12]([OH:14])=[O:13])[CH:8]=[C:7]2[OH:15]>C(O)C.[C].[Pd]>[OH:15][C:7]1[C:6]2[C:11](=[CH:2][C:3]([CH3:16])=[CH:4][CH:5]=2)[CH:10]=[C:9]([C:12]([OH:14])=[O:13])[CH:8]=1

参加物

4

反応物 1

HCID 67309189HCID 67309189、化合物

生成物 1

HCID 15539217HCID 15539217、化合物収率 98.9%

試薬・触媒・溶媒 2

HCID 178418390HCID 178418390、化合物触媒HCID 702Ethanol溶媒

実験手順

To a solution of 8-bromo-4-hydroxy-7-methylnaphthalene-2-carboxylic acid (0.45 g) in ethanol (8 mL) was added palladium-carbon (180 mg) in 3 parts, and the mixture was stirred at room temperature for 2 days under a hydrogen atmosphere. The insoluble material was removed by filtering through a Celite pad, and the filtrate was concentrated to give the title compound (0.32 g).

後処理

  1. customThe insoluble material was removed
  2. filtrationby filtering through a Celite pad
  3. concentrationthe filtrate was concentrated

出典と根拠

ORDレコード
ord-8a76776f05be4de3989f4d05de0a35ab
出典データセット
uspto-grants-2012_09
特許番号
US08263622B2

反応ノート

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