Triethylamine → HCID 86684866、化合物

HRID 238363

反応式

HRID 238363 の反応式
C(N(CC)CC)C.[CH3:8][N:9]1[C:13]([NH2:14])=[CH:12][CH:11]=[N:10]1.[CH:15]1[C:24]2[C:19](=[CH:20][CH:21]=[CH:22][CH:23]=2)[CH:18]=[C:17]2[C:25]([O:27][C:28](=O)[C:16]=12)=[O:26]>C1(C)C=CC=CC=1>[CH3:8][N:9]1[C:13]([N:14]2[C:28](=[O:27])[C:16]3[CH:15]=[C:24]4[CH:23]=[CH:22][CH:21]=[CH:20][C:19]4=[CH:18][C:17]=3[C:25]2=[O:26])=[CH:12][CH:11]=[N:10]1

参加物

5

反応物 3

HCID 8471TriethylamineHCID 69743Naphtho(2,3-c)furan-1,3-dioneHCID 1369272-Methyl-2H-pyrazol-3-ylamine

生成物 1

HCID 86684866HCID 86684866、化合物収率 87.6%

試薬・触媒・溶媒 1

HCID 1140Toluene溶媒

実験手順

Triethylamine (1.10 mL) was added to a toluene (14 mL) suspension that contained 1-methyl-1H-pyrazol-5-amine (400 mg) and 2,3-naphthalenedicarboxylic anhydride (816 mg), and the obtained solution was then heated to reflux for 2 hours. Thereafter, the reaction solution was cooled to a room temperature, and the precipitated solid was then collected by filtration. The collected solid was washed with ethyl acetate, so as to obtain the title compound (1.00 g) in the form of a colorless solid.

後処理

  1. temperaturethe obtained solution was then heated
  2. temperatureto reflux for 2 hours
  3. filtrationthe precipitated solid was then collected by filtration
  4. washThe collected solid was washed with ethyl acetate

出典と根拠

ORDレコード
ord-788b2b43ce4b47b5a5a35bfe3df41dd7
出典データセット
uspto-grants-2014_02
特許番号
US08642626B2

関連ノート

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