5-Methylsalicylic acid → 2-Hydroxy-5 methyl-N-[4-methyl-3-(trifluoromethyl)phenyl]benzamide

HRID 2384425

反応式

HRID 2384425 の反応式
[CH3:1][C:2]1[CH:10]=[C:6]([C:7]([OH:9])=O)[C:5]([OH:11])=[CH:4][CH:3]=1.[CH3:12][C:13]1[CH:19]=[CH:18][C:16]([NH2:17])=[CH:15][C:14]=1[C:20]([F:23])([F:22])[F:21]>>[OH:11][C:5]1[CH:4]=[CH:3][C:2]([CH3:1])=[CH:10][C:6]=1[C:7]([NH:17][C:16]1[CH:18]=[CH:19][C:13]([CH3:12])=[C:14]([C:20]([F:21])([F:22])[F:23])[CH:15]=1)=[O:9]

参加物

3

反応物 2

HCID 69735-Methylsalicylic acidHCID 27377154-Methyl-3-(trifluoromethyl)aniline

生成物 1

HCID 178602532-Hydroxy-5 methyl-N-[4-methyl-3-(trifluoromethyl)phenyl]benzamide収率 63.7%

実験手順

Using 5-methylsalicylic acid and 4-methyl-3-(trifluoromethyl)aniline as the raw materials, the same operation as the example 16 gave the title compound.

出典と根拠

ORDレコード
ord-1bf8a67346ff41d699cdb22bcf56784e
出典データセット
uspto-grants-2012_09
特許番号
US08263657B2

関連ノート

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