5-Methylsalicylic acid → 2-Hydroxy-N-[2-methoxy-5-(trifluoromethyl)phenyl]-5-methylbenzamide

HRID 2384428

反応式

HRID 2384428 の反応式
[CH3:1][C:2]1[CH:10]=[C:6]([C:7]([OH:9])=O)[C:5]([OH:11])=[CH:4][CH:3]=1.[CH3:12][O:13][C:14]1[CH:20]=[CH:19][C:18]([C:21]([F:24])([F:23])[F:22])=[CH:17][C:15]=1[NH2:16]>>[OH:11][C:5]1[CH:4]=[CH:3][C:2]([CH3:1])=[CH:10][C:6]=1[C:7]([NH:16][C:15]1[CH:17]=[C:18]([C:21]([F:23])([F:24])[F:22])[CH:19]=[CH:20][C:14]=1[O:13][CH3:12])=[O:9]

参加物

3

反応物 2

HCID 69735-Methylsalicylic acidHCID 6006372-Methoxy-5-(trifluoromethyl)aniline

生成物 1

HCID 178602452-Hydroxy-N-[2-methoxy-5-(trifluoromethyl)phenyl]-5-methylbenzamide収率 77.9%

実験手順

Using 5-methylsalicylic acid and 2-methoxy-5-(trifluoromethyl)aniline as the raw materials, the same operation as the example 16 gave the title compound.

出典と根拠

ORDレコード
ord-f46c004ed9d14f5888e859405bce5e41
出典データセット
uspto-grants-2012_09
特許番号
US08263657B2

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