5-Chlorosalicylic Acid → N-{2,5-Bis[(1,1-dimethyl)ethyl]phenyl}-5-chloro-2-hydroxybenzamide

反応式

[Cl:1][C:2]1[CH:10]=[C:6]([C:7]([OH:9])=O)[C:5]([OH:11])=[CH:4][CH:3]=1.[CH3:12][C:13]([C:16]1[CH:22]=[CH:21][C:20]([C:23]([CH3:26])([CH3:25])[CH3:24])=[CH:19][C:17]=1[NH2:18])([CH3:15])[CH3:14]>>[CH3:15][C:13]([C:16]1[CH:22]=[CH:21][C:20]([C:23]([CH3:26])([CH3:25])[CH3:24])=[CH:19][C:17]=1[NH:18][C:7](=[O:9])[C:6]1[CH:10]=[C:2]([Cl:1])[CH:3]=[CH:4][C:5]=1[OH:11])([CH3:12])[CH3:14]

参加物

反応物 2

HCID 94475-Chlorosalicylic Acid

HCID 6054882,5-di-tert-Butylaniline

生成物 1

HCID 66657248N-{2,5-Bis[(1,1-dimethyl)ethyl]phenyl}-5-chloro-2-hydroxybenzamide収率 75.7%

実験手順

Using 5-chlorosalicylic acid and 2,5-bis[(1,1-dimethyl)ethyl]aniline as the raw materials, the same operation as the example 16 gave the title compound.

出典と根拠

ORDレコード: ord-c514b2c628d84a9b8c5f3368e22ad540
出典データセット: uspto-grants-2012_09
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08263657B2

反応ノート

読み込み中…