Ethionamide → HCID 22249370、化合物
反応式
[CH3:1][CH2:2][C:3]1[CH:8]=[C:7]([C:9]([NH2:11])=S)[CH:6]=[CH:5][N:4]=1>CO.[Ni]>[CH2:2]([C:3]1[CH:8]=[C:7]([CH2:9][NH2:11])[CH:6]=[CH:5][N:4]=1)[CH3:1]参加物
4
実験手順
To a solution of 2-ethyl-4-thiopyridylamide (10 g) in MeOH (250 ml) was added Raney 2800 Nickel (5 g, Aldrich) in one portion. The mixture was stirred at RT for 2 days then at 60° C. for 16 h. The mixture was filtered, concentrated to provide the desired compound.
後処理
- waitat 60° C. for 16 h
- filtrationThe mixture was filtered
- concentrationconcentrated
出典と根拠
- ORDレコード
- ord-1f1a9a1d4a0a48b9962f5fc0ecdccfd1
- 出典データセット
- uspto-grants-2014_02
- 特許番号
- US08642624B2
反応ノート
読み込み中…