化工社化工社 化学情報印刷レポート · 研究参考用
Thionyl Chloride → 2-Fluoropyridine-3-carbonyl chloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Thionyl Chloride | HCID 24386 | — |
| 反応物 | 2-Fluoronicotinic acid | HCID 96089 | — |
| 生成物 | 2-Fluoropyridine-3-carbonyl chloride | HCID 21959582 | — |
反応手順
2-Fluoropyridine-3-carboxylic acid (7 g, Step C) was suspended in SOCl2 (100 mL). After heating under reflux for 2 h, the mixture became homogeneous. Excess SOCl2 was removed in vacuo to afford a brown solid as desired product.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08642624B2 |
| 出典データセット | uspto-grants-2014_02 |
| ORD ID | ord-9a43b48ccf53428fb07ec0624f068c33 |
| 出典メモ | uspto-grants-2014_02 |