関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Ethylene Glycol | HCID 174 | — |
| 反応物 | Ethanol | HCID 702 | — |
| 反応物 | Sodium Methoxide | HCID 10942334 | — |
| 反応物 | ethyl 3-(N-vinylformamido)propionate | HCID 19690337 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | 2-hydroxyethyl 3-(N-vinylformamido)propionate | HCID 19690342 | — |
反応手順
The apparatus of Example 2 was charged with 17.1 grams (0.1 mol) of ethyl 3-(N-vinylformamido)propionate, 6.2 grams (0.1 mol) of ethylene glycol, and 0.15 gram of 25% sodium methoxide in methanol solution. The mixture was stirred at 90° C. for 2 hours. No evolution of ethanol was observed during the reaction period. Heating for an additional hour at 135° C. also failed to generate a volatile coproduct which indicated no conversion to the desired product.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US05728878 |
|---|
| 出典データセット | uspto-grants-1998_03 |
|---|
| ORD ID | ord-9263fd3c38db4e7d8af1acf74087dcb3 |
|---|
| 出典メモ | uspto-grants-1998_03 |
|---|
