化工社化工社 化学情報印刷レポート · 研究参考用
2,4-Dichloropyrimidine → 5-(2-Chloro-pyrimidin-4-yl)-2-fluoro-benzaldehyde
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2,4-Dichloropyrimidine | HCID 77531 | — |
| 反応物 | (4-Fluoro-3-formylphenyl)boronic acid | HCID 2778651 | — |
| 生成物 | 5-(2-Chloro-pyrimidin-4-yl)-2-fluoro-benzaldehyde | HCID 24901981 | — |
反応手順
2,4 dichloropyrimidine and 3-formyl 4-fluorophenyl boronic acid were coupled following procedure A. LC-MS showed the product was >95% pure and had the expected M+H+ of 237.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08268822B2 |
| 出典データセット | uspto-grants-2012_09 |
| ORD ID | ord-5e9a4535f4724e70857854daaf2e163c |
| 出典メモ | uspto-grants-2012_09 |