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HRID 2387207作成日：2026年10月26日

2-Methyl-5-(morpholin-4-ylsulphonyl)benzeneboronic acid → 3-Amino-6-[2-methyl-5-(morpholine-4-sulfonyl)-phenyl]-pyrazine-2-carboxylic acid methoxy-methyl amide

https://huagongshe.com/reaction/2387207

反応式

関与物質

役割名称HCID仕込み量
反応物2-Methyl-5-(morpholin-4-ylsulphonyl)benzeneboronic acidHCID 44119554—
反応物3-Amino-6-(3,4-dichloro-phenyl)-pyrazine-2-carboxylic acid methoxy-methyl amideHCID 86634542—
生成物3-Amino-6-[2-methyl-5-(morpholine-4-sulfonyl)-phenyl]-pyrazine-2-carboxylic acid methoxy-methyl amideHCID 86634543—

反応手順

This compound is prepared in an analogous manner to intermediate B substituting 3,4 dichlorophenyl boronic acid with 2-methyl-5-(N-morpholinylsulfonyl) phenyl boronic acid in step 2. The title compound is obtained as an off-white solid. [M+H]+ 422.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US08268834B2
出典データセットuspto-grants-2012_09
ORD IDord-d102bace775e4209b0eab820f6a1c22b
出典メモuspto-grants-2012_09