Tributyl(2-phenylethynyl)stannane → 7-Hydroxy-2-phenyl-4-phenylethynyl-oxazolo[4,5-c]pyridine-6-carboxylic acid methyl ester
反応式
[CH3:1][O:2][C:3]([C:5]1[N:10]=[C:9](Br)[C:8]2[N:12]=[C:13]([C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=3)[O:14][C:7]=2[C:6]=1[OH:21])=[O:4].C([Sn](CCCC)(CCCC)[C:27]#[C:28][C:29]1[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=1)CCC>>[CH3:1][O:2][C:3]([C:5]1[N:10]=[C:9]([C:27]#[C:28][C:29]2[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=2)[C:8]2[N:12]=[C:13]([C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=3)[O:14][C:7]=2[C:6]=1[OH:21])=[O:4]参加物
3
実験手順
Prepared from 4-bromo-7-hydroxy-2-phenyl-oxazolo[4,5-c]pyridine-6-carboxylic acid methyl ester, example 3a, and tributyl(phenylethynyl)tin under conditions analogous to experimental example 3b. MS: (+) m/z 370.9 (M+1).
出典と根拠
- ORDレコード
- ord-492b07b493a3453ba2d77aa63b0e0af2
- 出典データセット
- uspto-grants-2012_09