N-(4-bromophenyl)-N-methylacetamide → tert-Butyl (4-{[4'-(acetyl-methyl-amino)-4-methoxy-biphenyl-3-ylmethyl]-amino}-cyclohexyl)-methyl-carbamate

関与物質

役割	名称	HCID	仕込み量
反応物	N-(4-bromophenyl)-N-methylacetamide	HCID 4324567	—
反応物	3-{[4-(BOC-methyl-amino)-cyclohexylamino]-methyl}-4-methoxy-benzene boronic acid	HCID 25208191	—
生成物	tert-Butyl (4-{[4'-(acetyl-methyl-amino)-4-methoxy-biphenyl-3-ylmethyl]-amino}-cyclohexyl)-methyl-carbamate	HCID 59683468	—

Boronic acid 4 (650 mg, 1.04 mmol) is coupled to aryl bromide 62 (238 mg, 1.04 mmol) using Method A to give the title compound.