関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | Malonic Acid | HCID 867 | — |
| 反応物 | Furfural | HCID 7362 | — |
| 反応物 | Piperidine | HCID 8082 | — |
| 溶媒 | Water | HCID 962 | — |
| 溶媒 | Pyridine | HCID 1049 | — |
| 生成物 | 2-Furanacrylic acid | HCID 643402 | 92% |
反応手順
To a mixture of 2-furfural (500 g, 5.20 mol) and malonic acid (595 g, 5.72 mol) in pyridine (500 mL) was added piperidine (50 mL, 0.505 mol) at room temperature, and the mixture was stirred at 100° C. for 3 hr. The reaction solution was poured into water (1 L) and acidified with 6M hydrochloric acid. The resulting precipitate was collected by filtration to give the title compound (660 g, yield 92%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US08273761B2 |
|---|
| 出典データセット | uspto-grants-2012_09 |
|---|
| ORD ID | ord-f4f5782bb6ab4fe5b912f3315f5b6e9d |
|---|
| 出典メモ | uspto-grants-2012_09 |
|---|
