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3-Bromo-2-methylpyridine → Tert-butyl{4-chloro-2-[(2-methylpyridin-3-yl)ethynyl]phenoxy}acetate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3-Bromo-2-methylpyridine | HCID 1201003 | — |
| 反応物 | Tert-butyl(4-chloro-2-ethynylphenoxy)acetate | HCID 56594381 | — |
| 生成物 | Tert-butyl{4-chloro-2-[(2-methylpyridin-3-yl)ethynyl]phenoxy}acetate | HCID 58521928 | — |
反応手順
Following the general method as outlined in Intermediate 19, starting from tert-butyl(4-chloro-2-ethynylphenoxy)acetate (Intermediate 3) and 3-bromo-2-methylpyridine (Synchem-OHG), the title compound was obtained as a yellow sticky solid after purification by preparative HPLC.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08273769B2 |
| 出典データセット | uspto-grants-2012_09 |
| ORD ID | ord-ccbd8eec367c44b3b021eaff2794922d |
| 出典メモ | uspto-grants-2012_09 |