4-Chloro-3-nitrophenyl methyl sulfone → 2-Chloro-5-methanesulfonylaniline

反応式

CS(C1C=CC(CCC)=C(C=1)N)(=O)=O.[Cl:15][C:16]1[CH:21]=[CH:20][C:19]([S:22]([CH3:25])(=[O:24])=[O:23])=[CH:18][C:17]=1[N+:26]([O-])=O>>[Cl:15][C:16]1[CH:21]=[CH:20][C:19]([S:22]([CH3:25])(=[O:24])=[O:23])=[CH:18][C:17]=1[NH2:26]

参加物

反応物 2

HCID 667964-Chloro-3-nitrophenyl methyl sulfone

HCID 585220065-(Methylsulfonyl)-2-propylaniline

生成物 1

HCID 18110852-Chloro-5-methanesulfonylaniline

実験手順

Following the general method as outlined in Intermediate 61, starting from 2-chloro-5-methylsulphonylnitrobenzene, the title compound was obtained as a dark green sticky solid in quantitative yield.

出典と根拠

ORDレコード: ord-67e59d5fa2ff4fafaf06bc9a5785f7da
出典データセット: uspto-grants-2012_09
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08273769B2

反応ノート

読み込み中…