2-Isopropenyl-5-(methylsulfonyl)aniline → 2-Isopropyl-5-(methylsulfonyl)aniline
反応式
CS(C1C=CC(CCC)=C(C=1)N)(=O)=O.[C:15]([C:18]1[CH:24]=[CH:23][C:22]([S:25]([CH3:28])(=[O:27])=[O:26])=[CH:21][C:19]=1[NH2:20])([CH3:17])=[CH2:16]>>[CH:15]([C:18]1[CH:24]=[CH:23][C:22]([S:25]([CH3:28])(=[O:26])=[O:27])=[CH:21][C:19]=1[NH2:20])([CH3:17])[CH3:16]参加物
3
実験手順
Following the general method as outlined in Intermediate 61, starting from 2-isopropenyl-5-(methylsulfonyl)aniline (Intermediate 89), the title compound was obtained as a green solid in 81% yield after purification by flash column chromatography (silica), eluting with cyclohexane containing increasing amounts of EtOAc.
出典と根拠
- ORDレコード
- ord-e86db1a49f5f49c3a923685c1533ac4a
- 出典データセット
- uspto-grants-2012_09
- 特許番号
- US08273769B2
反応ノート
読み込み中…