2-Bromo-5-methylsulfonylnitrobenzene → 4-(Methylsulfonyl)-2-nitro-1-vinylbenzene

反応式

Br[C:2]1[CH:7]=[CH:6][C:5]([S:8]([CH3:11])(=[O:10])=[O:9])=[CH:4][C:3]=1[N+:12]([O-:14])=[O:13].[CH:15](B1OC(C)(C)C(C)(C)O1)=[CH2:16]>>[CH3:11][S:8]([C:5]1[CH:6]=[CH:7][C:2]([CH:15]=[CH2:16])=[C:3]([N+:12]([O-:14])=[O:13])[CH:4]=1)(=[O:10])=[O:9]

参加物

反応物 2

HCID 20603662-Bromo-5-methylsulfonylnitrobenzene

HCID 52330122-Ethenyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

生成物 1

HCID 585219244-(Methylsulfonyl)-2-nitro-1-vinylbenzene

実験手順

Following the general method as outlined in Intermediate 20, starting from 2-bromo-5-methylsulfonylnitrobenzene and vinylboronic acid pinacol ester, the title compound was obtained as a brown oil in quantitative yield.

出典と根拠

ORDレコード: ord-c5ca50a4fa81470985545ba9d3a26aac
出典データセット: uspto-grants-2012_09
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08273769B2

反応ノート

読み込み中…