Formic Acid → HCID 21683295、化合物
反応式
Cl.Cl.[CH3:3][O:4][C:5]1[N:10]=[C:9]([NH2:11])[C:8]([NH2:12])=[CH:7][CH:6]=1.[CH:13](O)=O>>[CH3:3][O:4][C:5]1[N:10]=[C:9]2[N:11]=[CH:13][NH:12][C:8]2=[CH:7][CH:6]=1参加物
3
実験手順
10.19 g of 6-methoxypyridine-2,3-diamine dihydrochloride were dissolved in 100 ml formic acid and stirred under reflux for 72 h. The formic acid was evaporated under vacuum and the residue was dried under vacuum at 95° C. to give crude 5-methoxy-1H-imidazo[4,5-b]pyridine (as hydrochloride and/or as formic acid salt and/or as free base) that was used for the following step without further purification.
後処理
- temperatureunder reflux for 72 h
- customThe formic acid was evaporated under vacuum
- customthe residue was dried under vacuum at 95° C.
出典と根拠
- ORDレコード
- ord-861b197e53da4238a76a9264b8651928
- 出典データセット
- uspto-grants-2012_09
- 特許番号
- US08273890B2
反応ノート
読み込み中…