3-(4-Bromophenyl)-5-methyl-1,2,4-oxadiazole → 2-Methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-[1,1'-biphenyl]-4-carboxylic acid

HRID 2392660ノート

反応式

HRID 2392660 の反応式
Br[C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:12]=[C:11]([CH3:13])[O:10][N:9]=2)=[CH:4][CH:3]=1.B([C:17]1[CH:25]=[CH:24][C:20]([C:21]([OH:23])=[O:22])=[CH:19][C:18]=1[CH3:26])(O)O>>[CH3:26][C:18]1[CH:19]=[C:20]([C:21]([OH:23])=[O:22])[CH:24]=[CH:25][C:17]=1[C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:12]=[C:11]([CH3:13])[O:10][N:9]=2)=[CH:4][CH:3]=1

参加物

3

反応物 2

HCID 8235603-(4-Bromophenyl)-5-methyl-1,2,4-oxadiazoleHCID 221158924-Borono-3-methylbenzoic acid

生成物 1

HCID 189801352-Methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-[1,1'-biphenyl]-4-carboxylic acid

実験手順

The title compound was prepared from 3-(4-bromophenyl)-5-methyl-1,2,4-oxadiazole (1 g) and 4-borono-3-methylbenzoic acid (D74, 0.75 g) as a white solid (0.3 g, 24%) by the method described in Description 15.

出典と根拠

ORDレコード
ord-1e1253c6170e4c2a973f60b38b77a774
出典データセット
uspto-grants-1998_09
特許番号
US05801170

反応ノート

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