Hydrochloric Acid → 4-(2-Propen-1-yloxy)cyclohexanone
反応式
[CH2:1]([O:4][CH:5]1[CH2:14][CH2:13][C:8]2(OCC[O:9]2)[CH2:7][CH2:6]1)[CH:2]=[CH2:3].Cl.C(=O)([O-])O.[Na+]>CCOCC>[CH2:1]([O:4][CH:5]1[CH2:14][CH2:13][C:8](=[O:9])[CH2:7][CH2:6]1)[CH:2]=[CH2:3]参加物
5
実験手順
19.8 g of compound (11) (0.1 mmole) were stirred for 2 hours at room temperature with 120 ml ether and 40 ml of 6N hydrochloric acid. The mixture was then neutralised with sodium hydrogen carbonate, extracted three times with ether, and the ether solution was dried over sodium sulphate. After removing the solvent by distillation, 15.2 g of crude product were obtained; the product was purified with 3:1 diisopropyl ether/n-hexane via a silica gel column.
後処理
- extractionextracted three times with ether
- dry with materialthe ether solution was dried over sodium sulphate
- customAfter removing the solvent
- distillationby distillation
出典と根拠
- ORDレコード
- ord-dd41275c4d8046449c4bebbd28f00790
- 出典データセット
- uspto-grants-1998_09
- 特許番号
- US05801201
反応ノート
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