4-tert-Butylbenzoyl chloride → N-(4-t-Butylbenzoyl)-4-(2-bromoethyl)benzenesulfonamide

HRID 2392982ノート

反応式

HRID 2392982 の反応式
[Br:1][CH2:2][CH2:3][C:4]1[CH:9]=[CH:8][C:7]([S:10]([NH2:13])(=[O:12])=[O:11])=[CH:6][CH:5]=1.[C:14]([C:18]1[CH:26]=[CH:25][C:21]([C:22](Cl)=[O:23])=[CH:20][CH:19]=1)([CH3:17])([CH3:16])[CH3:15]>C1(C)C(C)=CC=CC=1>[C:14]([C:18]1[CH:19]=[CH:20][C:21]([C:22]([NH:13][S:10]([C:7]2[CH:6]=[CH:5][C:4]([CH2:3][CH2:2][Br:1])=[CH:9][CH:8]=2)(=[O:11])=[O:12])=[O:23])=[CH:25][CH:26]=1)([CH3:17])([CH3:15])[CH3:16]

参加物

4

反応物 2

HCID 743724-tert-Butylbenzoyl chlorideHCID 144850914-(2-Bromoethyl)benzenesulfonamide

生成物 1

HCID 18977847N-(4-t-Butylbenzoyl)-4-(2-bromoethyl)benzenesulfonamide

試薬・触媒・溶媒 1

HCID 7237O-Xylene溶媒

実験手順

A mixture of 26.41 g (0.10 mol) of 4-(2-bromoethyl)benzenesulfonamide, 19.67 g (0.10 mol) of 4-t-butylbenzoyl chloride and 160 ml of xylene was heated at reflux for 20 hrs. The hot solution was cooled and the solid which crystallized was collected, recrystallized from isopropanol collected, washed with ligroine and dried.

後処理

  1. temperaturewas heated
  2. temperatureat reflux for 20 hrs
  3. temperatureThe hot solution was cooled
  4. customthe solid which crystallized
  5. customwas collected
  6. customrecrystallized from isopropanol
  7. customcollected
  8. washwashed with ligroine
  9. customdried

出典と根拠

ORDレコード
ord-23c317b380a94066a46fe7c4f084d972
出典データセット
uspto-grants-1998_09
特許番号
US05804348

反応ノート

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