Methyl 1-benzothiophene-3-carboxylate → 1-Benzothiophen-3-ylmethanol
反応式
[S:1]1[CH:5]=[C:4]([C:6](OC)=[O:7])[C:3]2[CH:10]=[CH:11][CH:12]=[CH:13][C:2]1=2.[H-].[Al+3].[Li+].[H-].[H-].[H-]>CCOCC>[S:1]1[CH:5]=[C:4]([CH2:6][OH:7])[C:3]2[CH:10]=[CH:11][CH:12]=[CH:13][C:2]1=2参加物
4
実験手順
An ether solution (50 ml) of methyl benzo[b]thiophene-3-carboxylate (15 g) was added dropwise to a suspension of lithium aluminium hydride (3.5 g) in ether (100 ml) followed by reflux for 2 h. Usual work-up gave benzo[b]thiophen-3-yl methanol (13.5 g) as an oil.
後処理
- temperatureby reflux for 2 h
出典と根拠
- ORDレコード
- ord-e8e4a27c8cc549c3bce2feb7b117d673
- 出典データセット
- uspto-grants-1998_09
- 特許番号
- US05807871
反応ノート
読み込み中…