HCID 9798400、化合物 → HCID 18977165、化合物

HRID 2393749ノート

反応式

HRID 2393749 の反応式
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([C:7]([NH:9][CH2:10][CH2:11][CH2:12][CH2:13][C:14]2[CH:19]=[CH:18][C:17]([C:20]3[CH:21]=[CH:22][C:23](=[O:26])[NH:24][N:25]=3)=[CH:16][CH:15]=2)=[O:8])[CH:2]=1.[ClH:27].C(O)C>C(O)C>[ClH:27].[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([C:7]([NH:9][CH2:10][CH2:11][CH2:12][CH2:13][C:14]2[CH:19]=[CH:18][C:17]([C:20]3[CH:21]=[CH:22][C:23](=[O:26])[NH:24][N:25]=3)=[CH:16][CH:15]=2)=[O:8])[CH:2]=1

参加物

4

反応物 2

HCID 9798400HCID 9798400、化合物HCID 21887872Ethanol hydrochloride

生成物 1

HCID 18977165HCID 18977165、化合物

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

In hot ethanol (180 ml) was dissolved 8.9 g of 6-[4-(4-(pyridin-3-ylcarbonylamino)butyl)phenyl]pyridazin-3(2H)-one. A 18% hydrochloric acid-ethanol solution (10 ml) was added to the solution, and the mixture was left to stand at room temperature. Precipitated crystal was collected by filtration and washed with cold ethanol to obtain 9.3 g of 6-[4-(4-(pyridin-3-ylcarbonylamino)butyl)phenyl]pyridazin-3(2H)-one hydrochloride.

後処理

  1. waitthe mixture was left
  2. customto stand at room temperature
  3. customPrecipitated crystal
  4. filtrationwas collected by filtration
  5. washwashed with cold ethanol

出典と根拠

ORDレコード
ord-5863711c96ab4d5488285f496ae817ee
出典データセット
uspto-grants-1998_09
特許番号
US05808065

反応ノート

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