4-[3-(2-benzyloxyphenyl)-3-carbonyl-1(E)-propenyl]benzoate → Methyl 4-[2-(2-hydroxyphenyl)ethyl]-3-fluorobenzoate

HRID 2395013ノート

反応式

HRID 2395013 の反応式
C([O:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[CH:15]=[CH:16][C:17]1[CH:26]=[CH:25][C:20]([C:21]([O:23][CH3:24])=[O:22])=[CH:19][C:18]=1[F:27])C1C=CC=CC=1.C(OC1C=CC=CC=1C(=C=O)/C=C/C1C=CC(C([O-])=O)=CC=1)C1C=CC=CC=1.OC1C=CC=CC=1C(=C=O)CCC1C=CC(C(OC)=O)=CC=1>C(O)C>[OH:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[CH2:15][CH2:16][C:17]1[CH:26]=[CH:25][C:20]([C:21]([O:23][CH3:24])=[O:22])=[CH:19][C:18]=1[F:27]

参加物

5

反応物 3

HCID 189738944-[3-(2-benzyloxyphenyl)-3-carbonyl-1(E)-propenyl]benzoateHCID 18974023Methyl 4-[3-(2-hydroxyphenyl)-3-carbonylpropyl)benzoateHCID 54449624Methyl 4-[2-(2-benzyloxyphenyl)ethenyl)-3-fluorobenzoate

生成物 1

HCID 18973971Methyl 4-[2-(2-hydroxyphenyl)ethyl]-3-fluorobenzoate

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

Methyl 4-[2-(2-hydroxyphenyl)ethyl]-3-fluorobenzoate was synthesised from methyl 4-(2-(2-benzyloxyphenyl) ethenyl]-3-fluorobenzoate using the hydrogenation method described in Example 1 (for the conversion of 4-[3-(2-benzyloxyphenyl)-3-carbonyl-1(E)-propenyl]-benzoate to methyl 4-[3-(2-hydroxyphenyl)-3-carbonylpropyl)benzoate but using ethanol as the reaction solvent).

出典と根拠

ORDレコード
ord-a7606064646a4987935039f0e1b80515
出典データセット
uspto-grants-1998_09
特許番号
US05811459

反応ノート

読み込み中…