4-Chlorobenzenesulfonyl isocyanate → HCID 10095871、化合物
反応式
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([S:8]([N:11]=[C:12]=[O:13])(=[O:10])=[O:9])=[CH:4][CH:3]=1.[Cl:14][C:15]1[CH:23]=[CH:22][C:18]([C:19]([OH:21])=O)=[C:17]([NH:24][CH2:25][C:26]2[CH:27]=[N:28][CH:29]=[CH:30][CH:31]=2)[CH:16]=1>>[Cl:14][C:15]1[CH:16]=[C:17]2[C:18]([C:19](=[O:21])[N:11]([S:8]([C:5]3[CH:6]=[CH:7][C:2]([Cl:1])=[CH:3][CH:4]=3)(=[O:9])=[O:10])[C:12](=[O:13])[N:24]2[CH2:25][C:26]2[CH:27]=[N:28][CH:29]=[CH:30][CH:31]=2)=[CH:22][CH:23]=1参加物
3
実験手順
580 mg (2.68 mmol) of 4-chlorobenzenesulfonylisocyanate and 600 mg (2.28 mmol) of 4-chloro-2-(3-pyridylmethyl)aminobenzoic acid were treated in the same way as in Example 1 to obtain 175 mg of the above-identified compound (yield 16.6%). Properties: colorless crystal, Melting point: >190° C. (decomposition), PMR (δppm, DMSO-d6):5.29 (2H,s), 7.3-7.4 (2H,m), 7.39 (1H,s), 7.68 (1H,d), 7.79 (2H,d), 7.97 (1H,d), 8.20 (2H,d), 8.46 (1H,d), 8.57 (1H,d).
出典と根拠
- ORDレコード
- ord-d1e4ffefa49c4cb281ebc60fcb6c8141
- 出典データセット
- uspto-grants-1998_09
- DOI