Acetic Anhydride → HCID 23359034、化合物

HRID 2396955ノート

反応式

HRID 2396955 の反応式
[F:1][C:2]1[C:8]([CH3:9])=[C:7]([F:10])[C:6]([F:11])=[CH:5][C:3]=1[NH2:4].[C:12](OC(=O)C)(=[O:14])[CH3:13]>>[F:1][C:2]1[C:8]([CH3:9])=[C:7]([F:10])[C:6]([F:11])=[CH:5][C:3]=1[NH:4][C:12](=[O:14])[CH3:13]

参加物

3

反応物 2

HCID 7918Acetic AnhydrideHCID 146512532,4,5-Trifluoro-3-methylaniline

生成物 1

HCID 23359034HCID 23359034、化合物

実験手順

To 2,4,5-trifluoro-3-methylaniline (1 g) is added acetic anhydride (3 ml) at room temperature with stirring and the mixture is stirred for 15 minutes. The reaction mixture is poured into ice-water, extracted with dichloromethane, and the extract is washed with water and dried. The solvent is distilled off to give 2,4,5-trifluoro-3-methyl-N-acetylaniline (1.14 g), as white crystals.

後処理

  1. stirringthe mixture is stirred for 15 minutes
  2. extractionextracted with dichloromethane
  3. washthe extract is washed with water
  4. customdried
  5. distillationThe solvent is distilled off

出典と根拠

ORDレコード
ord-c2cebb32e5a141fab7892d3f84c4c075
出典データセット
uspto-grants-1996_02
特許番号
US05495020

反応ノート

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