化工社化工社 化学情報印刷レポート · 研究参考用
Propane sultone → Agn-PC-006bky
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Propane sultone | HCID 14264 | — |
| 反応物 | (3,5-Dimethoxyphenyl)methanamine | HCID 420973 | — |
| 溶媒 | Methyl Ethyl Ketone | HCID 6569 | — |
| 生成物 | Agn-PC-006bky | HCID 11300729 | — |
反応手順
To a solution of 3,5-dimethoxybenzylamine (2.5 g, 15.0 mmol) in 2-butanone (22 mL) was added 1,3-propane sultone (1.95 g, 15.8 mmol). The mixture was stirred at reflux for 2 hours. The reaction mixture was cooled to room temperature. The solid was collected by filtration, washed with acetone (2×25 mL), and dried in vacuo. This allowed the isolation of compound BA, 2.89 g (67%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08642801B2 |
| 出典データセット | uspto-grants-2014_02 |
| ORD ID | ord-7dd78b3b7325462089c01f762ca08271 |
| 出典メモ | uspto-grants-2014_02 |