Bromine → 2-Amino-5-bromo-4-fluoropyridin-3-ol

反応式

[NH2:1][C:2]1[C:7]([OH:8])=[C:6]([F:9])[CH:5]=[CH:4][N:3]=1.[Br:10]Br>>[NH2:1][C:2]1[C:7]([OH:8])=[C:6]([F:9])[C:5]([Br:10])=[CH:4][N:3]=1

参加物

反応物 2

HCID 24408Bromine

HCID 214366942-Amino-4-fluoropyridin-3-ol

生成物 1

HCID 214366732-Amino-5-bromo-4-fluoropyridin-3-ol

実験手順

When 2-amino-4-fluoro-3-pyridinol and bromine in a 1:1 molar ratio are passed through a glass tube heated at 350°, and the exit gases condensed and distilled, there is obtained 2-amino-5-bromo-4-fluoro-3-pyridinol.

後処理

temperatureheated at 350°
customthe exit gases condensed
distillationdistilled

出典と根拠

ORDレコード: ord-0b290a49377b4edf86b6b4a7816a1b38
出典データセット: uspto-grants-1977_05
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04022897

反応ノート

読み込み中…