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Benzoyl chloride, 3,4,5-trimethoxy- → 6-(3,4,5-Trimethoxybenzamido)-2-methyl-1,2,3,4-tetrahydroisoquinoline
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Benzoyl chloride, 3,4,5-trimethoxy- | HCID 78282 | — |
| 反応物 | 2-Methyl-1,2,3,4-tetrahydroisoquinolin-6-amine | HCID 21436741 | — |
| 生成物 | 6-(3,4,5-Trimethoxybenzamido)-2-methyl-1,2,3,4-tetrahydroisoquinoline | HCID 216593 | — |
反応手順
6-Amino-2-methyl-1,2,3,4-tetrahydroisoquinoline was reacted with 3,4,5-trimethoxybenzoyl chloride as in Example 16 to yield 6-(3,4,5-trimethoxybenzamido)-2-methyl-1,2,3,4-tetrahydroisoquinoline. It was recovered as the HCl salt; m.p. 233.5°-235° C. after purification in methanol.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04022900 |
| 出典データセット | uspto-grants-1977_05 |
| ORD ID | ord-bec9069431bb45fc91c40e6826400640 |
| 出典メモ | uspto-grants-1977_05 |