2-Bromobenzoyl chloride → Benzamide, 2-bromo-N-(1,2,3,4-tetrahydro-2-methylisoquinolin-5-yl)-

HRID 2397947ノート

反応式

HRID 2397947 の反応式
[NH2:1][C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[CH2:4][CH2:5][N:6]([CH3:12])[CH2:7]2.[Br:13][C:14]1[CH:22]=[CH:21][CH:20]=[CH:19][C:15]=1[C:16](Cl)=[O:17]>>[Br:13][C:14]1[CH:22]=[CH:21][CH:20]=[CH:19][C:15]=1[C:16]([NH:1][C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[CH2:4][CH2:5][N:6]([CH3:12])[CH2:7]2)=[O:17]

参加物

3

反応物 2

HCID 235422-Bromobenzoyl chlorideHCID 141712692-Methyl-1,2,3,4-tetrahydroisoquinolin-5-amine

生成物 1

HCID 37749Benzamide, 2-bromo-N-(1,2,3,4-tetrahydro-2-methylisoquinolin-5-yl)-

実験手順

5-Amino-2-methyl-1,2,3,4-tetrahydroisoquinoline was reacted with 2-bromobenzoyl chloride according to the procedure of Example 19 to yield 5-(2-bromobenzamido)-2-methyl-1,2,3,4-tetrahydroisoquinoline; m.p. 206.5°-208.5° C. after purification from ethanol.

出典と根拠

ORDレコード
ord-6799126ece69465687acfedbd42c029b
出典データセット
uspto-grants-1977_05
特許番号
US04022900

反応ノート

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