6-Chloro[1,3]dioxolo[4,5-f][1,3]benzothiazole → HCID 178527754、化合物
反応式
Cl[C:2]1[S:3][C:4]2[CH:10]=[C:9]3[O:11][CH2:12][O:13][C:8]3=[CH:7][C:5]=2[N:6]=1.NC(N)=[S:16]>C(O)C>[SH:16][C:2]1[S:3][C:4]2[CH:10]=[C:9]3[O:11][CH2:12][O:13][C:8]3=[CH:7][C:5]=2[N:6]=1参加物
4
実験手順
The product from Step 2 (0.67 g) and thiourea (0.26 g) were mixed in ethanol (20 cm3) and stirred and heated to reflux under an atmosphere of nitrogen for 18 hr. The pale yellow solid which precipitated was filtered from the solution at ambient temperature, washed with ethanol and sucked to dryness to give the required product. 1H NMR (DMSO): δ7.26(1H,s); 6.80(1H,s); 6.02(2H,s); mp 265° C. (dec); M+ =211.
後処理
- temperatureheated
- temperatureto reflux under an atmosphere of nitrogen for 18 hr
- customThe pale yellow solid which precipitated
- filtrationwas filtered from the solution at ambient temperature
- washwashed with ethanol
出典と根拠
- ORDレコード
- ord-0d8b9693e20043679f50682ffbbf8374
- 出典データセット
- uspto-grants-1995_09
- 特許番号
- US05451594
反応ノート
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