3-(Dimethylamino)propyl chloride hydrochloride → HCID 58530420、化合物
反応式
[C:1]([C:3]1[CH:26]=[CH:25][C:6]([CH2:7][N:8]2[C:16]3[C:11](=[CH:12][C:13](/[CH:17]=[C:18]4/[C:19](=[O:24])[NH:20][C:21](=[O:23])[S:22]/4)=[CH:14][CH:15]=3)[CH:10]=[CH:9]2)=[C:5]([C:27]([F:30])([F:29])[F:28])[CH:4]=1)#[N:2].Cl.[CH3:32][N:33]([CH3:38])[CH2:34][CH2:35][CH2:36]Cl>>[CH3:32][N:33]([CH3:38])[CH2:34][CH2:35][CH2:36][N:20]1[C:19](=[O:24])/[C:18](=[CH:17]/[C:13]2[CH:12]=[C:11]3[C:16](=[CH:15][CH:14]=2)[N:8]([CH2:7][C:6]2[CH:25]=[CH:26][C:3]([C:1]#[N:2])=[CH:4][C:5]=2[C:27]([F:29])([F:30])[F:28])[CH:9]=[CH:10]3)/[S:22][C:21]1=[O:23]参加物
3
実験手順
4-({5-[(Z)-{3-[3-(Dimethylamino)propyl]-2,4-dioxo-1,3-thiazolidin-5-ylidene}methyl]-1H-indol-1-yl}methyl)-3-(trifluoromethyl)benzonitrile was prepared from [(5Z)-5-({1-[4-cyano-2-(trifluoromethyl)benzyl]-1H-indol-5-yl}methylidene)-2,4-dioxo-1,3-thiazolidine (from Example 246) and 3-(dimethylamino)propyl chloride hydrochloride following General Procedure H.
出典と根拠
- ORDレコード
- ord-2e41e60568a343fa86117d8cb4eb0ddb
- 出典データセット
- uspto-grants-2014_08
- 特許番号
- US08796256B2
反応ノート
読み込み中…