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2-(Benzylamino)pyridine → N-(3-{4-[(Benzyl-pyridin-2-yl-amino)-methyl]-phenyl}-pyrazin-2-yl)-2-chloro-benzenesulfonamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-(Benzylamino)pyridine | HCID 23362 | — |
| 反応物 | HCID 57444254 | HCID 57444254 | — |
| 生成物 | N-(3-{4-[(Benzyl-pyridin-2-yl-amino)-methyl]-phenyl}-pyrazin-2-yl)-2-chloro-benzenesulfonamide | HCID 11960665 | 35% |
反応手順
Following the general method as outlined in Example 1 (Method B), starting from N-{3-[4-(chloromethyl)phenyl]pyrazin-2-yl}-2-(chloro) benzenesulfonamide (Intermediate 8), and 2-benzylaminopyridine, the title compound was isolated as a yellow solid in 35% yield (94% purity by HPLC).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08796280B2 |
| 出典データセット | uspto-grants-2014_08 |
| ORD ID | ord-6cf549fa2c954c6c921392dc272dfe8c |
| 出典メモ | uspto-grants-2014_08 |