Ammonium Hydroxide → 6-Aminopyridine-3-sulfonamide
反応式
Cl[C:2]1[N:7]=[CH:6][C:5]([S:8]([NH2:11])(=[O:10])=[O:9])=[CH:4][CH:3]=1.[NH4+:12].[OH-]>[Cl-].[Na+].O>[NH2:12][C:2]1[N:7]=[CH:6][C:5]([S:8]([NH2:11])(=[O:10])=[O:9])=[CH:4][CH:3]=1参加物
4
反応条件
- 温度
- 110 °C
実験手順
6-Chloropyridine-3-sulfonic acid amide (200 mg, 1 mmol) was placed in a sealed tube with 2 mL 28% aq. NH4OH and heated to 110° C. for 4 h. The mixture was diluted with brine and the title compound was collected as a solid (120 mg, 67%).
後処理
- customthe title compound was collected as a solid (120 mg, 67%)
出典と根拠
- ORDレコード
- ord-99ba472de0b444089f6d7083198c06b6
- 出典データセット
- uspto-grants-2014_08
- 特許番号
- US08796313B2
反応ノート
読み込み中…