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Methanol → 3-methoxy-9-oxo-9H-indeno[1,2-b]pyrazine-2-carbonitrile
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Methanol | HCID 887 | — |
| 反応物 | 9-oxo-9H-indeno(1,2-b)pyrazine-2,3-dicarbonitrile | HCID 292929 | — |
| 生成物 | 3-methoxy-9-oxo-9H-indeno[1,2-b]pyrazine-2-carbonitrile | HCID 16065353 | 126.5% |
反応手順
To a suspension of 1 (1.10 g, 4.7 mmol) in MeOH (47 ml) sodium (110 mg) was added and the mixture was stirred at room temperature for 16 hours. The precipitate was filtered, washed with EtOH and dried under vacuum, yielding 3 (1.03 g, 93%) as yellow-green solid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08648076B2 |
| 出典データセット | uspto-grants-2014_02 |
| ORD ID | ord-b40012b19977406f87d5a10b4b6e4989 |
| 出典メモ | uspto-grants-2014_02 |