化工社化工社 化学情報印刷レポート · 研究参考用
Hydrochloric Acid → 5-Methyl-2-(pyridin-4-yl)benzoic acid hydrochloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | Methyl 5-methyl-2-(pyridin-4-yl)benzoate | HCID 86680841 | — |
| 溶媒 | Acetic Acid | HCID 176 | — |
| 生成物 | 5-Methyl-2-(pyridin-4-yl)benzoic acid hydrochloride | HCID 86680842 | — |
反応手順
A mixture of methyl 5-methyl-2-(pyridin-4-yl)benzoate (8.8 g), 6 N hydrochloric acid (65 mL) and acetic acid (100 mL) was heated under reflux overnight. The solvent was evaporated under reduced pressure, and the obtained solid was washed with ethyl acetate to give the title compound (6.6 g).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08648079B2 |
| 出典データセット | uspto-grants-2014_02 |
| ORD ID | ord-e51704f3495d47bdb5219c94a8b48ddf |
| 出典メモ | uspto-grants-2014_02 |