Hydrochloric Acid → [2,4'-Bipyridine]-3-carboxylic acid dihydrochloride

HRID 240393ノート

反応式

HRID 240393 の反応式
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([C:7]([O:9]CC)=[O:8])[C:2]=1[C:12]1[CH:17]=[CH:16][N:15]=[CH:14][CH:13]=1.[ClH:18]>>[ClH:18].[ClH:18].[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([C:7]([OH:9])=[O:8])[C:2]=1[C:12]1[CH:17]=[CH:16][N:15]=[CH:14][CH:13]=1

参加物

3

反応物 2

HCID 313Hydrochloric AcidHCID 46317743Ethyl [2,4'-bipyridine]-3-carboxylate

生成物 1

HCID 84819756[2,4'-Bipyridine]-3-carboxylic acid dihydrochloride

実験手順

A solution of ethyl 2,4′-bipyridine-3-carboxylate (14.1 g) in 6 N hydrochloric acid (200 mL) was heated under reflux overnight. The solvent was evaporated under reduced pressure, to the obtained residue was added toluene, and the solvent was again evaporated under reduced pressure to give the title compound (16.4 g).

後処理

  1. temperatureunder reflux overnight
  2. customThe solvent was evaporated under reduced pressure, to the obtained residue
  3. additionwas added toluene
  4. customthe solvent was again evaporated under reduced pressure

出典と根拠

ORDレコード
ord-0985a229539f494894619095dc9732a6
出典データセット
uspto-grants-2014_02
特許番号
US08648079B2

反応ノート

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