Ethyl Acetate → 3-(S)-Methyl-pentanedioic acid mono-(2-trimethylsilanyl-ethyl) ester
反応式
[CH3:1][Si:2]([CH3:17])([CH3:16])[CH2:3][CH2:4][O:5][C:6](=[O:15])[CH2:7][C@@H:8]([CH3:14])[CH2:9][C:10]([O:12]C)=[O:11].O.[OH-].[Li+].[Cl-].[NH4+].C(OCC)(=O)C>C(O)(C)C.O>[CH3:17][Si:2]([CH3:1])([CH3:16])[CH2:3][CH2:4][O:5][C:6](=[O:15])[CH2:7][C@@H:8]([CH3:14])[CH2:9][C:10]([OH:12])=[O:11]参加物
7
実験手順
To the solution of 3-(S)-Methyl-pentanedioic acid methyl ester 2-trimethylsilanyl-ethyl ester in iso-propanol and water was added lithium hydroxide monohydrate and stirred for two hours at RT. The reaction mixture was treated with saturated ammonium chloride and ethyl acetate. The product was purified by column chromatography.
後処理
- customThe product was purified by column chromatography
出典と根拠
- ORDレコード
- ord-8a7c15a82800408a8c70620c287dc923
- 出典データセット
- uspto-grants-2014_08
- 特許番号
- US08809382B2
反応ノート
読み込み中…