Chlorosuccinimide → 6-Chloro-5-phenyl-1,2,4-triazin-3-amine

反応式

[C:1]1([C:7]2[N:8]=[C:9]([NH2:13])[N:10]=[N:11][CH:12]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Cl:14]N1C(=O)CCC1=O>>[Cl:14][C:12]1[N:11]=[N:10][C:9]([NH2:13])=[N:8][C:7]=1[C:1]1[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

参加物

反応物 2

HCID 31398Chlorosuccinimide

HCID 970815-Phenyl-1,2,4-triazin-3-amine

生成物 1

HCID 866761156-Chloro-5-phenyl-1,2,4-triazin-3-amine収率 92.4%

実験手順

6-Chloro-5-phenyl-1,2,4-triazin-3-amine (0.38 g, 65%) was prepared from 5-phenyl-1,2,4-triazin-3-amine (0.50 g, 1.99 mmol) and N-chlorosuccinimide (0.50 g, 3.7 mmol) according to the general procedure of Preparation 3.

後処理

customaccording to the general procedure of Preparation 3

出典と根拠

ORDレコード: ord-6eb20a47203c49ec9871366e2014e2a9
出典データセット: uspto-grants-2014_08
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08809525B2

反応ノート

読み込み中…