Hydrochloric Acid → HCID 66989456、化合物
反応式
C(OC([NH:8][C:9]1[S:13][C:12]([C:14]([O:16][CH2:17][CH:18]2[CH2:23][CH2:22][N:21]([CH2:24][C:25]3[S:29][C:28]([C:30]4[CH:35]=[CH:34][CH:33]=[CH:32][N:31]=4)=[N:27][CH:26]=3)[CH2:20][CH2:19]2)=[O:15])=[C:11]([CH3:36])[C:10]=1[C:37]#[N:38])=O)(C)(C)C.[ClH:39]>CO.ClCCl>[ClH:39].[ClH:39].[ClH:39].[NH2:8][C:9]1[S:13][C:12]([C:14]([O:16][CH2:17][CH:18]2[CH2:19][CH2:20][N:21]([CH2:24][C:25]3[S:29][C:28]([C:30]4[CH:35]=[CH:34][CH:33]=[CH:32][N:31]=4)=[N:27][CH:26]=3)[CH2:22][CH2:23]2)=[O:15])=[C:11]([CH3:36])[C:10]=1[C:37]#[N:38]参加物
5
実験手順
The compound prepared in Example 223 (0.026 g) was suspended in methanol (2 mL) and dichloromethane (2 mL). Hydrogen chloride solution (4 M in 1,4-dioxane) (3.0 mL) was added and the reaction mixture stirred at room temperature overnight. The reaction mixture was concentrated under reduced pressure to afford the title compound (0.027 g), which was used without further purification possessing the following physical data.