2-(Pyridin-2-yl)-1,3-thiazole-5-carbaldehyde → HCID 66989148、化合物

反応式

[NH2:1][C:2]1[C:7]([C:8]#[N:9])=[C:6]([O:10][CH2:11][CH3:12])[N:5]=[C:4]([C:13]([NH:15][CH2:16][C:17]2([O:23][CH3:24])[CH2:22][CH2:21][NH:20][CH2:19][CH2:18]2)=[O:14])[CH:3]=1.[N:25]1[CH:30]=[CH:29][CH:28]=[CH:27][C:26]=1[C:31]1[S:32][C:33]([CH:36]=O)=[CH:34][N:35]=1>>[NH2:1][C:2]1[C:7]([C:8]#[N:9])=[C:6]([O:10][CH2:11][CH3:12])[N:5]=[C:4]([C:13]([NH:15][CH2:16][C:17]2([O:23][CH3:24])[CH2:18][CH2:19][N:20]([CH2:36][C:33]3[S:32][C:31]([C:26]4[CH:27]=[CH:28][CH:29]=[CH:30][N:25]=4)=[N:35][CH:34]=3)[CH2:21][CH2:22]2)=[O:14])[CH:3]=1

参加物

反応物 2

HCID 534037722-(Pyridin-2-yl)-1,3-thiazole-5-carbaldehyde

HCID 66990903HCID 66990903、化合物

生成物 1

HCID 66989148HCID 66989148、化合物

実験手順

According to the same procedure described in Example 101, starting with the compound prepared in Example 260 instead of the compound prepared in Example 226 and the compound prepared in Example 139 instead of 2-phenylthiazole-5-carbaldehyde, the title compound having the following physical data was obtained.

出典と根拠

ORDレコード: ord-a68be4b4052347da8df2087040ef7179
出典データセット: uspto-grants-2014_08
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08809538B2

反応ノート

読み込み中…

参加物