2-(Pyridin-2-yl)-1,3-thiazole-5-carbaldehyde → HCID 66989601、化合物

反応式

[NH2:1][C:2]1[C:7]([C:8]#[N:9])=[C:6]([O:10][CH2:11][CH3:12])[N:5]=[C:4]([C:13]([NH:15][CH2:16][C@@H:17]2[CH2:22][CH2:21][NH:20][CH2:19][C@H:18]2[OH:23])=[O:14])[CH:3]=1.[N:24]1[CH:29]=[CH:28][CH:27]=[CH:26][C:25]=1[C:30]1[S:31][C:32]([CH:35]=O)=[CH:33][N:34]=1>>[NH2:1][C:2]1[C:7]([C:8]#[N:9])=[C:6]([O:10][CH2:11][CH3:12])[N:5]=[C:4]([C:13]([NH:15][CH2:16][C@@H:17]2[CH2:22][CH2:21][N:20]([CH2:35][C:32]3[S:31][C:30]([C:25]4[CH:26]=[CH:27][CH:28]=[CH:29][N:24]=4)=[N:34][CH:33]=3)[CH2:19][C@H:18]2[OH:23])=[O:14])[CH:3]=1

参加物

反応物 2

HCID 534037722-(Pyridin-2-yl)-1,3-thiazole-5-carbaldehyde

HCID 66990398HCID 66990398、化合物

生成物 1

HCID 66989601HCID 66989601、化合物

実験手順

According to the same procedure described in Example 101, starting with the compound prepared in Example 268 and the compound prepared in Example 139, the title compound having the following physical data was obtained.

出典と根拠

ORDレコード: ord-59b674022f794c57aa84c84f44f07086
出典データセット: uspto-grants-2014_08
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08809538B2

反応ノート

読み込み中…