4-Aminoquinoline-2-carboxylic acid → HCID 66989751、化合物
反応式
[NH2:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N:5]=[C:4]([C:12]([OH:14])=O)[CH:3]=1.[C:15]1([C:21]2[CH:25]=[C:24]([CH2:26][N:27]3[CH2:32][CH2:31][CH:30]([CH2:33][NH2:34])[CH2:29][CH2:28]3)[O:23][N:22]=2)[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1>>[NH2:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N:5]=[C:4]([C:12]([NH:34][CH2:33][CH:30]2[CH2:29][CH2:28][N:27]([CH2:26][C:24]3[O:23][N:22]=[C:21]([C:15]4[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=4)[CH:25]=3)[CH2:32][CH2:31]2)=[O:14])[CH:3]=1参加物
3
実験手順
According to the same procedure described in Example 225, using the compound prepared in Example 275 instead of 4-amino-5-cyano-6-ethoxypicolinic acid, and using 1-{1-[(3-phenyl-5-isoxazolyl)methyl]-4-piperidinyl}methanaminethe compound prepared in Example 9 instead of tert-butyl 4-(aminomethyl)piperidine-1-carboxylate the title compound having the following physical data was obtained.
出典と根拠
- ORDレコード
- ord-c372f36007f64d2c94e9c9a1bce97c3f
- 出典データセット
- uspto-grants-2014_08
- 特許番号
- US08809538B2
反応ノート
読み込み中…