3-Cyano-2-pyridone → 955399-19-6
反応式
[O:1]=[C:2]1[C:7]([C:8]#[N:9])=[CH:6][CH:5]=[CH:4][NH:3]1.[NH4+]=[S:11]>CO>[O:1]=[C:2]1[C:7]([C:8](=[S:11])[NH2:9])=[CH:6][CH:5]=[CH:4][NH:3]1参加物
3
試薬・触媒・溶媒 1
反応条件
- 温度
- 130 °C
実験手順
To a suspension of 2-oxo-1,2-dihydropyridine-3-carbonitrile (0.211 g) in methanol (14 mL) was added a 40% aqueous solution of ammonium sulfide (0.50 mL). The reaction mixture was heated at 130° C. in a microwave reactor for 2 hours. The reaction mixture was concentrated. The residue obtained was triturated with methanol and the solid filtered to obtain the title compound (0.174 g) having the following physical data.
後処理
- concentrationThe reaction mixture was concentrated
- customThe residue obtained
- customwas triturated with methanol
- filtrationthe solid filtered
出典と根拠
- ORDレコード
- ord-d76337db382d4ab8aaa875a0da4c4660
- 出典データセット
- uspto-grants-2014_08
- 特許番号
- US08809538B2
反応ノート
読み込み中…