化工社化工社 化学情報印刷レポート · 研究参考用
Acetic Acid → 2-Acetoxypropionic Acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Acetic Acid | HCID 176 | — |
| 反応物 | Lactic Acid | HCID 612 | — |
| 反応物 | Sulfuric Acid | HCID 1118 | — |
| 溶媒 | Toluene | HCID 1140 | — |
| 生成物 | 2-Acetoxypropionic Acid | HCID 79041 | 92% |
反応手順
Reflux a mixture of 2-hydroxy-propionic acid (480 ml, 85% in water) and sulfuric acid (2 mL) in acetic acid (2500 mL) and toluene (300 mL) for overnight. After removal of solvent under vacuum, purify the residue by distillation to give 2-acetoxy-propionic acid (550 g, 92%) as colorless oil. 1H NMR (CDCl3, 400 MHz): δ 9.27 (brs, 1H), 5.10 (m, 1H), 2.13 (s, 3H), 1.53 (d, J=7.2, 3H).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08648081B2 |
| 出典データセット | uspto-grants-2014_02 |
| ORD ID | ord-454818cf5b8a4bdebc359436e7990c79 |
| 出典メモ | uspto-grants-2014_02 |